Each player sends 2 cards from their hand to the GY and draws 2 cards.
Sending 2 cards from the hand to the GY is NOT a cost.
Sending a card to the GY is not the same as discarding it.
Dragon-Type monsters sent to the GY do not count towards Super Rejuvenation.
Dark World monsters will not activate, since they must be discarded to the GY.
If a player is unable to draw 2 cards (because they have 1 or 0 in Deck), they lose the duel.
if a player does not have 2 cards in hand to send to the GY, then neither player sends any cards from the hand to the GY nor draws cards.
This card CAN be activated while Macro Cosmos is active. The cards are removed from play instead.
You CANNOT ACTIVATE Hand Destruction:
if either player has fewer than 2 cards remaining in their Deck.
while Protector of the Sanctuary is face-up on the field.
if activating (playing it face-up) it would cause you to have fewer than 2 cards in your hand.
"Hand Destruction" cannot be activated if either play has 1 or less cards in their hand and/or remaining in their Deck. If you have "Hand Destruction" and 1 other card in your hand, you cannot activate "Hand Destruction".
If either player has 1 or less cards in their hand when "Hand Destruction" resolves, its effect disappears. If either player has 1 or less cards remaining in their Deck, they lose the Duel when they are unable to draw a card.
"Hand Destruction" cannot be activated while "Protector of the Sanctuary" is face-up on the field.
If "Macro Cosmos" is face-up on the field, "Hand Destruction" can still be activated. The cards sent from the hand to the GY are removed from play instead.